Search different genes to identify which tissues have a ramp sequence. The color of each cell represents the normalized expression level of the gene in the tissue. A darker blue indicates higher expression. When a tissue does not have a ramp sequence in the gene, a "-" is marked in the cell. Data can be filtered by gene, dataset, ramp presence, and normalized expression. To clear the currently displayed genes, on the "Gene" filter check the "All" box, then uncheck it, and then press "Apply." A ramp presence of "Uncertain" indicates that the original FASTA gene sequence could not be run through the ExtRamp algorithm.

From the Human Protein Atlas website: "For each of the three transcriptomics datasets (HPA, GTEx and FANTOM5), the average TPM value of all individual samples for each human tissue or human cell type was used to estimate the gene expression level. To be able to combine the datasets into consensus transcript expression levels, a pipeline was set up to normalize the data for all samples. In brief, all TPM values per sample were scaled to a sum of 1 million TPM (denoted pTPM) to compensate for the non-coding transcripts that had been previously removed. Next, all TPM values of all the samples within each data source (HPA human tissues, HPA blood cells, GTEx, and FANTOM5 respectively) were TMM normalized, followed by Pareto scaling of each gene within each data source. Tissue data from the three transcriptomics datasets were subsequently integrated using batch correction through the removeBatchEffect function of R package Limma, using the data source as a batch parameter. The blood RNA-seq dataset was not limma-adjusted. The resulting transcript expression values, denoted Normalized Expression, were calculated for each gene in every sample."

Search different genes to identify which cell types have a ramp sequence as well as information such as gene expression level and measurement reliability. When a cell type does not have a ramp sequence in the gene, a "-" is marked in the cell. To clear the currently displayed genes, on the "Gene" filter check the "All" box, then uncheck it, and then press "Apply." Information can be filtered by gene, tissue, cell type, reliability, ramp presence, or expression level. Expression levels have been switched from "High," "Medium," "Low," and "Not Detected" to 3, 2, 1, and 0 respectively to implement Tableau's color gradient feature. Reliability scores as defined by the Human Protein Atlas are based on RNA expression level correlation with antibody staining, independent antibody validation, knockdown of the target protein, matching the antibody stainings signal with GFP-tagged proteins, and evidence from literature.